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KMID : 0363219920300050644
Korean Journal of Dermatology
1992 Volume.30 No. 5 p.644 ~ p.650
Clinicopathological observation of the patients with Isoniazid Responsive Inflammatory Nodules on the Legs


Lee Sung-Kyu

Abstract
We performed a clinicopathological study of nineteen patients with chronic inflammatory nodose lesions of the legs which responded to the treatment with isoniazid.
@ES The results were summarized as follows;
@EN 1. Seven patients had a personal or family history of tuberculosis and all patients showed a high tuberculin sensitivity. but no one showed the evidence of active pulmonary tuberculosis.
2. The inflammatory nodules and swelling of the legs were resolved within 12 months in all cases. Resolution of the nodules was more rapid than that of leg swelling.
3. The clinical characteristics of the patients with chronic inflammatory nodules were the same as those to fhe cases with erythema nodosum or erythema induratum reported previously in Korea. The basic histopathologic process of inflammatory
nodules
seemed to be vasculitis. (Kor J Dermatol 1992;30(5):644-650)
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